Fifth's disease

Fifth's disease

Fifth's disease is caused by a virus. Only rarely is it more serious. Fifth's disease most often occurs in elementary school children. Once your child gets fifth's disease, they most likely won't get it again.

Symptoms of fifth's disease are:

  • low-grade fever
  • fatigue
  • face rash that looks like "slapped cheeks"
  • a lacy rash on arms and legs that appears after the fever

The symptoms appear between 4 and 14 days after your child is exposed to the virus. The virus is not spread after the rash appears.

Antibiotics will not help treat fifth's disease. The virus will have to run its course.

When to call your health care provider

If you are pregnant, the risk to your unborn baby is slight. But, if you think you have been exposed to fifth's disease, call your health care provider.

Related resources

Source: Allina Health's Patient Education, Guide for the Care of Children: Ages Birth to 5, sixth edition, ped-ah-91554
First Published: 02/01/2010
Last Reviewed: 11/16/2022