
She underwent six months of chemotherapy and immunotherapy with the hope of a complete response, meaning the treatment would destroy all the cancer. But a small amount remained, and a surgeon had to remove it.
“Women with residual disease after preoperative chemotherapy are more likely to harbor residual cancer cells somewhere else in their bodies and, therefore, are more likely to relapse. The purpose of chemotherapy after preoperative chemotherapy and surgery is to eliminate these cells,” said Dr. Perez.
The study
Gina agreed to participate in a randomized clinical trial called ASCENT-05, which compares two treatment approaches for patients with triple-negative breast cancer who still had cancer remaining after chemotherapy and immunotherapy. Allina Health Cancer Institute is one of 11 sites across the United States participating in this phase III trial. Researchers hope the study will identify the most effective way to prevent the cancer from returning.
“If I could be part of changing the standard of care so that recurrence doesn’t happen, put my name down. Let’s do it,” said Gina.
Both treatment approaches in the trial included the use of Keytruda, a prescribed immunotherapy medication, and one of two chemotherapy treatments. One group received Xeloda, a chemotherapy pill that is currently the standard treatment for patients with triple-negative breast cancer. The other group was given Trodelvy, a newer type of chemotherapy that researchers believe may be more effective at preventing cancer from returning in patients like Gina.
“To my great satisfaction, Gina was randomized to the experimental arm of the study and was treated with Trodelvy plus Keytruda,” said Dr. Perez.
Gina had to go through another six months of chemotherapy, something she considered necessary, but daunting.
“I'm just young. I was too young. I was like, ‘Let's go!’ Do I want to lose my hair and go through all that again? Absolutely not, but I also don’t want to die before I’m 40. So, let’s do what we have to do,” said Gina.
What’s next
Today, Gina describes herself as healthy and is back working as a nurse in Minnesota. Although Gina will continue to be monitored by her care team, her next big milestone comes on Dec. 29, 2026. That’s when she will reach three years since the completion of treatment.
“The highest risk of relapse is in the first three years after treatment,” said Dr. Perez. “That risk is lower during years four and five, much lower during year six and extremely low after 10 years.”
Gina’s message
Gina wants all women to know they’re never too young to pay attention to changes in their breasts.
“Get your mammograms,” added Dr. Perez. “If you have a lump, don’t ignore it. Let somebody know. It is better to know now than in the future. If you know today, you’re going to be more curable than six months from now.”
Because Gina paid attention and took action, she’s here today preparing to marry her fiancé on a beach in 2027.
“I’ve always been very much peace, love and positive thoughts. You have to think positive. That’s been my mindset before cancer. It’s my mindset during and mindset after,” said Gina. “Live day by day and enjoy it.”