Skip to main content

Current research studies

  • The following research studies are underway

    Neuro-oncology

    1. Trusheim, Bruns, McDonald: A Phase II Clinical Trial Evaluating DCVax®-Brain, Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen For The Treatment Of Glioblastoma Multiforme (GBM)
    2. Trusheim, Bruns: Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221 (DCVax-L EAP).
    3. Banerji, Trusheim, Bruns, McDonald, Oswood: Intra-arterial Chemotherapy in Recurrent High-Grade Glioma: Impact on Local Control, Patient Survival, and Health-Related Quality of Life
    4. Trusheim, Bruns, McDonald: A Phase 1/2 Study of the Combination of Indoximod and Temozolomide for Adult Patients with Temozolomide-Refractory Primary Malignant Brain Tumors
    5. Banerji, Trusheim, Bruns: Pilot study of circulating microRNAs in plasma as biomarkers of treatment response in recurrent high grade glioma patients treated with intra-arterial chemotherapy
    6. Trusheim, Banerji, Bruns: Care patterns and outcomes for patients with glioblastoma treated at Abbott Northwestern Hospital
    7. Trusheim, Bruns, McDonald: A Phase III randomized double-blind, controlled study of ICT-107 with maintenance temozolomide (TMZ) in newly diagnosed glioblastoma following resection and concomitant TMZ chemoradiotherapy.
    8. Trusheim, Bruns, Nagib, Uittenbogaard: A Phase 2/3 Randomized, Open-Label Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma

    Neuroradiology

    1. Oswood M, Banerji N : iMRI-Guided Resection of Brain Tumors at ANW Hospital: An Analytical Review
    2. Oswood M, Banerji N, McDonald W: Role of Novel Functional Magnetic Resonance Imaging and Pathologic Features to Address the Diagnostic Dilemma of Pseudoprogression in Treatment of Newly Diagnosed Glioblastomas

    Neuro-pathology

    1. McDonald W, Banerji N: Pituitary Adenoma Tissue Microarray Project: Validation Phase
    2. McDonald W, Banerji N: Loss of Immunohistochemical staining for succinate dehydrogenase subunit B in pituitary adenomas

    Neurovascular/Stroke

    1. Asaithambi G, Castle A: Does Telestroke Implementation Help Achieve Door to Needle Time Metrics in Acute Ischemic Stroke?
    2. Asaithambi G, Castle A: Intravenous Alteplase use in Stroke Mimics via Telemedicine
    3. Corry JJ: Utility of Procalcitonin for Diagnosis of Bacterial Infection Related Systemic Inflammatory Response in the Acute Neurologic Injury Population: A Retrospective Cohort Study
    4. Delgado J, Kayan Y, Crandall B: EffectiveNess and Safety of Small Aneurysm COiling trial (NANO)
    5. Delgado J, Kayan Y, Young M: The Randomized, Concurrent Controlled Trial to Assess the Penumbra System’s Safety and Effectiveness in the Treatment of Acute Stroke (THERAPY)
    6. Delgado J, Kayan Y. Systematic Evaluation of Patients Treated with Neurothrombectomy Devices for Acute Ischemic Stroke Registry (STRATIS)
    7. Delgado J, Kayan Y: Humanitarian Use of Neuroform Stent
    8. Delgado J, Kayan Y: Humanitarian Use of the LVIS Device.
    9. Delgado J, Kayan Y: New Generation Hydrogel Endovascular Aneurysm Treatment Trial (HEAT)
    10. Delgado J, Kayan Y: Pivotal Study of the MicroVention, Inc. Neurovascular Self-Expanding Retrievable Stent System LVIS in the Treatment of Wide-Necked Intracranial Artery Aneurysms (LVIS)
    11. Delgado J, Kayan Y: Prospective, Multi-Center, Single-Arm Study of the Reverse Medical Barrel Vascular Reconstruction Device for Adjunctive Treatment to Embolic Coils for Wide-Neck, Intracranial, Bifurcation/Branching Aneurysms of Middle Cerebral and Basilar Arteries (The BARREL Study)
    12. Delgado J, Kayan Y: The WEB Intrasaccular Therapy Study (WEB-IT)
    13. Delgado J, Kayan Y: The Wingspan Stent System and Gateway PTA Balloon Catheter, a Humanitarian Use Device
    14. Hanson S, Corry J, Asaithambi G, Patel S, Monita J: Platelet –oriented Inhibition in New TIA and Minor Ischemic Stroke Trial (POINT)
    15. Hanson S, Corry J, Asaithambi G, Patel S, Monita J: TIA clinic:  Changing an inpatient evaluation to an urgent, safe, subspecialty outpatient evaluation.  Partnership with Clinical Excellence Research Center (CERC), Stanford University.
    16. Kayan Y, Banerji N, Fease J, Delgado J: Study of vasospasm in Subarachnoid hemorrhage patients with Advanced Sequence MRI (SPASM)
    17. Kayan Y, Delgado J, Crandall B: An Aneurysm Coiling Efficiency Study of the Penumbra Coil 400 System (ACE)
    18. Kayan Y, Delgado J,: Pivotal Study of the MicroVention Flow Re-Directional Endoluminal Device Stent System in the Treatment of Intracranial Aneurysms (FRED)
    19. Kayan Y, Delgado J: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated with the Penumbra Coil 400 (CARE)
    20. Kayan Y, Delgado J: A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke
    21. Young M, Tarrel R, Roohani P: Acute Stroke Or Transient IsChaemic Attack TReated with Aspirin or Ticagrelor and Patient OutcomES (SOCRATES)
    22. Young M, Tarrel R, Roohani P: Platelet –oriented Inhibition in New TIA and Minor Ischemic Stroke Trial (POINT)
    23. Young M, Tarrel R, Roohani P: Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the Efficacy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate versus Acetylsalicylic Acid in Patients with Embolic Stroke of Undetermined Source (RESPECT-ESUS)