Health Guide
Drug Guide

Levoleucovorin (By injection)

Levoleucovorin (lee-voe-loo-koe-VOE-rin)

Given to prevent the harmful effects of methotrexate (a cancer medicine) in patients with bone cancer (osteosarcoma). Also given to patients who receive too much methotrexate for other conditions. Also used in combination with 5-fluorouracil (Adrucil®) to relieve and prevent symptoms of advanced metastatic (cancer that has already spread) cancer of the colon and rectum. This medicine acts in the body like folic acid (vitamin B9).

Brand Name(s):

Fusilev

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to levoleucovorin or similar medicines such as folic acid (Folvite®) and folinic acid. You should not receive this medicine if you have certain blood problems such as anemia caused by a lack of vitamin B12.

How to Use This Medicine:

Injectable

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 12/12/2016

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