Health Guide
Drug Guide

Acetaminophen/guaifenesin/phenylephrine (By mouth)

Acetaminophen (a-seet-a-MIN-oh-fen), Guaifenesin (gwye-FEN-e-sin), Phenylephrine (fen-il-EF-rin)

Treats cold, flu, and allergy symptoms such as stuffy nose, fever, and mild aches, relieves sinus headaches, and helps loosen mucus.

Brand Name(s):

CCP, Good Sense Sinus Congestion & Pain Severe, Mucinex Fast-Max Cold & Sinus, Rite Aid Severe Sinus Congestion & Pain Relief, Sudafed PE Pressure+Pain+Mucus, Sudafed PE Triple Action, Theraflu Warming Relief Cold & Chest Congestion, Tylenol Cold Head Congestion Severe, Tylenol Sinus Congestion & Pain Severe, Tylenol Sinus Severe Day

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to acetaminophen, guaifenesin, phenylephrine, or any other pain, cough, or cold medicines. Do not give any over-the-counter (OTC) cough and cold medicine to a child younger than 4 years.

How to Use This Medicine:

Liquid, Long Acting Tablet, Tablet

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/12/2016

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Thomson & A.D.A.M