Health Guide
Drug Guide

Pioglitazone/metformin (By mouth)

Metformin Hydrochloride (met-FOR-min hye-droe-KLOR-ide), Pioglitazone Hydrochloride (pye-oh-GLI-ta-zone hye-droe-KLOR-ide)

Used together with proper diet and exercise to help control blood sugar in patients with type 2 diabetes.

Brand Name(s):

Actoplus Met, Actoplus Met XR

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to pioglitazone or metformin. You should not use this medicine if you have bladder cancer, severe heart failure, severe liver disease, severe kidney disease, type 1 diabetes, metabolic acidosis (acid in the blood), or diabetic ketoacidosis (ketones in the blood). You should talk with your doctor about temporarily stopping this medicine if you are going to have major surgery or an x-ray procedure with an injection of dyes (contrast agents) into your vein.

How to Use This Medicine:

Tablet, Long Acting Tablet

If a dose is missed:

How to Store and Dispose of This Medicine:

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 12/12/2016

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Thomson & A.D.A.M