Health Guide
Drug Guide

Levobunolol (Ophthalmic route)

Pronunciation:

lee-voe-BUE-noe-lol

Brand Names:

Dosage Forms:

Classifications:

Therapeutic

Antiglaucoma

Pharmacologic

Beta-Adrenergic Blocker, Nonselective

Uses of This Medicine:

Levobunolol is used alone or together with other medicines to treat increased pressure in the eye that is caused by open-angle glaucoma or a condition called ocular (eye) hypertension. This medicine is a beta-blocker .

This medicine is available only with your doctor's prescription .

Before Using This Medicine:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Children

Appropriate studies have not been performed on the relationship of age to the effects of levobunolol in the pediatric population. Safety and efficacy have not been established .

Older adults

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of levobunolol in the elderly .

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast-feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Other interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Proper Use of This Medicine:

Shake the medicine well just before each use .

To use the eye drops (solution):

If your doctor ordered two different eye medicines to be used together, wait several minutes before using the second medicine. This will help prevent the second medicine from “washing out” the first one .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using This Medicine:

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .

If itching, redness, swelling, or other signs of eye or eyelid irritation occur, stop using this medicine and check with your doctor. These signs may mean that you are allergic to this medicine .

Levobunolol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing .

This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests .

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery .

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
Burning or stinging in eye
drainage from the eye
redness, swelling, and/or itching of eye and eyelid
Less common
Blurred vision
chest pain or discomfort
confusion
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
shortness of breath
slow or irregular heartbeat
sweating
unusual tiredness or weakness
Rare
Eye pain
headache
hives or welts
itching skin
redness of skin
shakiness and unsteady walk
skin rash
tearing
unsteadiness, trembling, or other problems with muscle control or coordination
unusual drowsiness, dullness, or feeling of sluggishness
Incidence not determined
Blistering, peeling, loosening of skin
blue lips, fingernails, or skin
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chills
cough
decreased urine output
diarrhea
difficult or labored breathing
difficulty in chewing, swallowing, or talking
dilated neck veins
disturbed color perception
double vision
drooping eyelids
extreme fatigue
fast, pounding, or racing heartbeat or pulse
fever
halos around lights
hoarseness
inability to speak
irregular, fast or slow, or shallow breathing
irritation
joint pain, stiffness, or swelling
muscle pain
muscle weakness
night blindness
no blood pressure or pulse
noisy breathing
overbright appearance of lights
red skin lesions, often with a purple center
seeing double
seizures
severe numbness, especially on one side of the face or body
severe or sudden headache
severe tiredness
slurred speech
sore throat
sores, ulcers, or white spots in mouth or on lips
stopping of heart
swelling of eyelids, face, lips, hands, fingers, feet, or lower legs
temporary blindness
tightness in chest
troubled breathing
tunnel vision
unconsciousness
weakness in arm and/or leg on one side of the body, sudden and severe
weight gain
wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined
Decreased interest in sexual intercourse
discouragement
feeling sad or empty
inability to have or keep an erection
irritability
lack of appetite
lack or loss of strength
loss in sexual ability, desire, drive, or performance
loss of interest or pleasure
nausea
stuffy nose
tiredness
trouble concentrating
trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Last Updated: 10/12/2016

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