Health Guide
Drug Guide

Chenodeoxycholic acid

What is it?

Chenodeoxycholic acid is a bile acid that is used to treat gallstones.

Other names for chenodeoxycholic acid include: Chenodiol, Chenic Acid, and CDCA.

Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.

Before Using:

Tell your doctor if you


Talk with your caregiver about how much chenodeoxycholic acid you should take. The amount depends on the strength of the medicine and the reason you are taking chenodeoxycholic acid. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.

To store this medicine:

Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.


Side Effects:

Call your doctor right away if you have any of these side effects:

Other Side Effects:

You may have the following side effects, but this medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.


1. Way LW: The National Cooperative Gallstone Study and chenodiol. Gastroenterology 1983; 84(3):648-651.

2. Bennion LJ & Grundy SM: Risk factors for the development of cholelithiasis in man. N Engl J Med 1978; 299:1161-1167, 1221-1227.

3. Product Information: Chenix(R), chenodiol. Reid-Rowell, Marietta, GA; 1987.

4. USPDI: Drug Information for the Health Care Professional, 20th ed. Micromedex Inc, Englewood, CO; 2000.

5. Zak RA, Marks JW & Schoenfield LJ: Current status of chenodeoxycholic acid (chenodiol) therapy of cholesterol gallstones. Sem Liver Dis 1983; 3:132-145.

6. Pomare EW, Heaton KKW, Low-Beer TS et al: The effect of wheat bran, upon bile salt metabolism and upon the lipid composition of bile in gallstone patients. Am J Dig Dis 1976; 21(7):521-526.

7. Schoenfield LJ & Lachin JM: Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: The National Cooperative Gallstone Study. A controlled study of efficacy and safety. Ann Intern Med 1981; 95:257-282.

8. Dowling RH: Chenodeoxycholic acid therapy of gallstones. Clin Gastroenterol 1977; 6:141-163.

9. Fisher RL, Anderson DW, Boyer JL et al: A prospective morphologic evaluation of hepatic toxicity of chenodeoxycholic acid in patients with cholelithiasis: The National Cooperative Gallstone Study. Hepatology 1982; 2:187-201.


Last Updated: 9/15/2016

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