Health Guide
Drug Guide

Yohimbe

What is it?

Yohimbe is an herbal medicine used to treat male impotence (sexual dysfunction). Yohimbe is not recommended for women, children, elderly people, and those with mental illness.

Other names for yohimbe include: Johimbe and Yohimbine

Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.

Before Using:

Tell your doctor if you

Dosage:

Talk with your caregiver about how much Yohimbe you should take. The amount depends on the strength of the medicine and the reason you are taking yohimbe. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.

To store this medicine:

Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.

Drug and Food Interactions:

Do not take yohimbe without talking to your doctor first if you are taking:

Warnings:

Side Effects:

Call your doctor right away if you have any of these side effects:

Other Side Effects:

You may have the following side effects, but this medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.

References:

1. Gean CJ & Meyers FH: Pocket Drug Guide, 2nd ed. Williams & Wilkins, Baltimore, MD; 1997.

2. Tyler VE: The New Honest Herbal. GF Stickley Co, Philadelphia, PA; 1987.

3. Fleming T (ed): PDR for Herbal Medicines. Medical Economics Company, Montvale, NJ; 1998.

4. Anon: Yohimbine hydrochloride. Mosby Inc; 1998. Available at: http://www.Rxlist.com (cited 1/6/00).

5. McGuffin M, Hobbs C, Upton R et al: Botanical Safety Handbook. CRC Press, Boca Raton, FL; 1997.

6. Lacomblez L, Bensimon G, Isnard F et al: Effect of yohimbine on blood pressure in patients with depression and orthostatic hypotension induced by clomipramine. Clin Pharmacol Ther 1989; 45(3):241-251.

7. Charney DS, Heninger GR, & Sternberg DE: Assessment of alpha-2 adrenergic autoreceptor function in humans: effect of oral yohimbine. Life Sci 1982; 30(23):2033-2041.

8. Tyler VE: Herbs of Choice: The Therapeutic use of phytomedicinals. Pharmaceutical Products Press, New York, NY; 1991.

9. Price J & Grunhaus LJ: Treatment of clomipramine-induced anorgasmia with yohimbine: a case report. J Clin Psychiatry 1990; 51(1):32-33.

10. Morales A, Surridge DH, & Marshall PG: Yohimbine for treatment of impotence in diabetes. N Engl J Med 1981; 305(20):1221.

11. Landis E & Shore E: Yohimbine-induced bronchospasm. Chest 1989; 96(6): 1424.

12. Fetrow CW & Avila JR: Professional's Handbook of Complementary and Alternative Medicines. Springhouse Corporation, Springhouse, PA; 1999:689-692.

13. Charney DS, Heninger GR & Redmond DE: Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine. Life Sci 1983; 33(1):19-29.

14. McDougle CJ, Krystal JH, Price LH et al: Noradrenergic response to acute ethanol administration in healthy subjects: comparison with intravenous yohimbine. Psychopharmacology 1995; 118(2):127-135.

15. Price LH, Charney DS & Heninger GR: Three cases of manic symptoms following yohimbine administration. Am J Psychiatry 1984; 141(10):1267-1268.

16. Gear RW, Gordon NC, Heller PH et al: Enhancement of morphine analgesia by the alpha2-adrenergic antagonist yohimbine. Neuroscience 1995; 66(1):5-8.

17. Jordan J & Sharma AM: Potential for sibutramine-yohimbine interaction. Lancet 2003; 361(9371):1826.

18. Product Information: Yohimbine hydrochloride. PDR Generics, Medical Economics, MontvYohimbine hydrochloride. PDR Generics, Medical Economics, Montvale, NJ, 1997.

19. Goldberg MR & Robertson D: Yohimbine: a pharmacological probe for study of the alpha2-adrenoreceptor. Pharmacol Rev 1983; 35:143-180.

20. Goldstein DS, Grossman E, Listwak S et al: Sympathetic reactivity during a yohimbine challenge test in essential hypertension. Hypertension 1991; 18 (Suppl 3): 40-48.

21. Grossman E, Rosenthal T, Peleg E et al: Oral yohimbine increased blood pressure and sympathetic nervous outflow in hypertensive patients. J Cardiovasc Pharmacol 1993; 22:22-26.

22. Rosen MI, Kosten TR & Kreek MJ: The effects of naltrexone maintenance on the response to yohimbine in healthy volunteers. Biol Psychiatry 1999; 45(12):1636-1645.


Last Updated: 9/15/2016

Thomson Micromedex. All rights reserved.

Thomson & A.D.A.M