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Medicine you should stop taking before knee replacement surgery

  • Blood thinner medicines

    If you are taking any kind of blood thinner medicine, call your primary care provider to find out if or when your medicine should be stopped before surgery.

    Examples of medicines that can thin your blood are:

    • aspirin
    • Plavix®
    • warfarin (Coumadin® or Jantoven®)
    • Xarelto®
    • Pradaxa®
    • heparin
    • Lovenox®
    • Arixtra™

    Herbal medicines

    Herbal or natural medicines can cause side effects or interfere with other medicines.

    You should check with your primary care provider to see if any herbal medicines you are taking need to be stopped before surgery.

    There are 15 commonly used herbals and supplements that have some known side effects that may occur when taken with other medicines. Check with your primary care provider if you are taking:

    • fish oil
    • Vitamin E
    • St. John's wort
    • echinacea
    • ginkgo (ginkgo biloba)
    • ephedra (ma-huang)
    • ginseng
    • licorice
    • garlic
    • valerian
    • ginger
    • feverfew
    • saw palmetto
    • goldenseal
    • kava-kava

    Pain medicines

    You should stop taking the following types of pain medicine (non-steriodal anti-inflammatory agent) two to seven days before surgery.

    Medicines Not To Take Before Surgery

    Please note: These are general guidelines for medicines not to take before surgery. Your primary care provider will tell you when to stop taking any medicines before surgery. Follow all directions you receive.

    Do not take any of the listed diabetes medicines the morning of surgery. Talk with your health care provider who manages your diabetes before you stop taking your medicine. You may have other directions.

    Medicines Not To Take Before Surgery

    Please note: These are general guidelines for medicines not to take before surgery. Your primary care provider will tell you when to stop taking any medicines before surgery. Follow all directions you receive.

    Do not take any of the listed diabetes medicines the morning of surgery. Talk with your health care provider who manages your diabetes before you stop taking your medicine. You may have other directions.

    Do not take any of the listed diabetes medicines the morning of surgery. Talk with your health care provider who manages your diabetes before you stop taking your medicine. You may have other directions.

    Medicines Not To Take Before Surgery

    Please note: These are general guidelines for medicines not to take before surgery. Your primary care provider will tell you when to stop taking any medicines before surgery. Follow all directions you receive.

    Type of medicine Brand name examples Generic name examples General guidelines

    Blood thinner medicine

    Ecotrin® or Bufferin®
    Plavix®
    Coumadin®or Jantoven®
    Xarelto®
    Pradaxa®

    aspirin
    clopidogrel
    warfarin
    rivaroxaban
    dabigatran

    Do not take 7 days before surgery.

    Talk with your health care provider who manages your blood thinners before you stop taking your medicine. You may need to take other medicines when you are not taking them.

    Nonsteroidal and anti-inflammatory (NSAID) medicine

    Motrin® or Advil®
    Aleve®

    ibuprofen
    naproxen

    Do not take 3 days before surgery.

    Blood glucose medicine

    Micronase®
    Glucotrol®
    Amaryl®
    Glucophage®
    Insulin

    glyburide
    glipizide
    glimepiride
    metformin
    insulin

    Herbal products, vitamins or minerals

    Do not take any herbal supplement, product, vitamin or mineral at least 5 days before surgery.


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