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Botulism antitoxin (Injection)

Botulism Equine Heptavalent Antitoxin (ABCDEFG) (BOT-ue-lizm EE-kwyne hep-ta-VAY-lent an-ti-TOX-in ABCDEFG)

Treats botulism, a serious infection that causes muscle paralysis.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to botulism antitoxin.

How to Use This Medicine:


  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have asthma, hay fever, seasonal allergies, or diabetes. Tell your doctor if you have had an allergic reaction to horses or horse blood products.
  • Check with your doctor right away if you have muscle or joint pain, a fever, swollen lymph glands, or a rash within 1 to 3 weeks after you are given this medicine. These can be symptoms of a delayed allergic reaction (serum sickness).
  • Check with your doctor or nurse right away if you have a headache, fever, chills, trouble breathing, nausea, vomiting, lightheadedness, or muscle and joint pain while you are receiving this medicine. Your caregiver may need to treat these symptoms or make changes to your treatment.
  • This medicine contains maltose, which can interfere with some blood glucose monitoring systems. Talk to your doctor if your test your blood glucose or use insulin.
  • This medicine is made from horse plasma. It is possible that horse blood products may spread viruses to people who receive them, although this has not been reported. Talk to your doctor if you have any symptoms that concern you.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Cough, trouble breathing
  • Fast, pounding, or uneven heartbeat
  • Fever or chills, rash, joint pain, or swollen lymph glands in the neck, armpit, or groin
  • Headache
  • Lightheadedness, dizziness, or fainting
  • Nausea or vomiting

If you notice these less serious side effects, talk with your doctor:

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  • Rapid weight gain, swelling in your hands, ankles, or feet

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 4/4/2014

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