Ezogabine (By mouth)
Used together with other medicines to control partial seizures. Belongs to a class of medicines called anticonvulsants.
Brand Name(s):There may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have had an allergic reaction to ezogabine.
How to Use This Medicine:
- Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
- You may take this medicine with or without food.
- Swallow the tablet whole. Do not break, crush, dissolve, or chew it.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using carbamazepine (Tegretol®), digoxin (Lanoxin®), or phenytoin (Dilantin®).
- Tell your doctor if you are also using atropine, dicyclomine, glycopyrrolate, scopolamine, Bentyl®, Robinul®, or Transderm Scop®.
- Do not drink alcohol while you are using this medicine.
Warnings While Using This Medicine:
- It is important to tell your doctor if you become pregnant while taking this medicine. Your doctor may want you to join the North American Antiepileptic Drug Pregnancy Registry. The registry is used by pregnant patients who are taking this medicine.
- Make sure your doctor knows if you are breastfeeding, or if you have kidney disease, liver disease, congestive heart failure, heart disease, heart rhythm problem (QT prolongation, long QT syndrome), enlarged prostate, trouble emptying your bladder, or mineral imbalance (such as low magnesium or potassium in the blood). Tell your doctor if you have depression, mental illness, or a history of alcohol or drug abuse. Tell your doctor if you are on kidney dialysis.
- If you develop any unusual or strange thoughts and behavior while using this medicine, be sure to discuss it with your doctor. Other changes might be confusion, worsening of depression, hallucinations (seeing, hearing, or feeling things that are not there), suicidal thoughts, and unusual excitement, nervousness, or irritability.
- This medicine may cause urinating problems. Call you doctor right away if you have trouble emptying your bladder, a weak urine system, pain while urinating, or if you are unable to start urinating.
- This medicine may make you dizzy, drowsy, or have blurred or double vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert or not able to see well.
- This medicine can cause changes in heart rhythms, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects in some patients. Contact your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or uneven heartbeats.
- Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
- This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
- Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. Blood tests may be needed to check for unwanted effects.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Anxiety, confusion, or depression.
- Decrease in how much or how often you urinate, painful urination.
- Fast, pounding, or uneven heartbeat.
- Loss of seizure control.
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
- Red or dark brown urine.
- Seeing, hearing, or feeling things that are not there.
- Swelling in your hands, ankles, or feet.
- Unusual thoughts or behavior.
- Unusual tiredness or weakness.
If you notice these less serious side effects, talk with your doctor:
- Blurred or double vision.
- Clumsiness, unsteadiness, or problems with balance, speech, or walking.
- Cough or cold-like symptoms.
- Dizziness or lightheadedness.
- Memory problems.
- Nausea, vomiting, constipation, or stomach pain or upset.
- Sleepiness or unusual drowsiness.
- Spinning sensation.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088Last Updated:
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