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Ceftaroline (Injection)

Ceftaroline Fosamil (sef-TAR-oh-leen FOS-a-mil)

Treats certain skin infections and community-acquired bacterial pneumonia (CABP) caused by bacteria. Belongs to a class of drugs called cephalosporin antibiotics.

Brand Name(s):

Teflaro

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to ceftaroline or to other cephalosporin antibiotics such as cefaclor, cefadroxil, cefuroxime, cephalexin, Cefzil®, or Omnicef®.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • This medicine is usually given every 12 hours for 5 to 14 days or until your body responds to the medicine. Each treatment usually takes at least an hour.
  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, anemia, or a history of colitis (inflammation in gut) or severe diarrhea. Tell your doctor if you have had an allergic reaction to penicillin antibiotics such as amoxicillin, amoxicillin/clavulanate, penicillin, Amoxil®, Augmentin®, Trimox®, or Veetids®.
  • This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have itching; hives; hoarseness; shortness of breath; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after you receive this medicine.
  • Ask your doctor before you take any medicine to stop severe diarrhea. Check with your doctor right away if the diarrhea continues. Diarrhea may occur 2 months or more after you stop taking this medicine.
  • Hemolytic anemia may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you have back, leg, or stomach pains; bleeding gums; chills; dark urine; difficulty with breathing; fever; general body swelling; headache; loss of appetite; nausea or vomiting; nosebleeds; pale skin; sore throat; unusual tiredness or weakness; or yellowing of the eyes or skin.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash.
  • Diarrhea that may contain blood.
  • Severe stomach pain, cramps, or bloating.
  • Shortness of breath, tiredness, uneven heartbeat, or yellowing of your skin or the whites of your eyes.
  • Unusual bleeding, bruising, or weakness.

If you notice these less serious side effects, talk with your doctor:

  • Mild diarrhea, constipation, nausea, or vomiting.
  • Mild skin rash.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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