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Liraglutide (Injection)

Liraglutide (lir-a-GLOO-tide)

Treats type 2 diabetes.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to liraglutide, or if you have a family history of medullary thyroid cancer or a condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). You should not use this medicine if you have diabetic ketoacidosis or type I diabetes.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under the skin of your stomach, thighs, or upper arms.
  • If you use insulin in addition to this medication, do not mix them into the same syringe. You may give the shots in the same area (such as your stomach), but do not give the shots right next to each other.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Allow the medicine to warm at room temperature before you inject it. Do not use this medicine if it looks cloudy or has changed color.
  • You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
  • Use a new needle and syringe each time you inject your medicine.
  • Never share medicine pens with others under any circumstances. It is not safe for one pen to be used by more than one person. Sharing needles or pens can result in transmission of infection.
  • Follow carefully the meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Exercise regularly and test for sugar in your blood or urine as directed.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

If a dose is missed:

  • If you miss a dose of this medicine, use it as soon as you remember. Then take your next daily dose as usual on the following day. Never take extra medicine to make up for a mixed dose. If you miss a dose of this medicine for 3 days or more, call your doctor to talk about how to restart your treatment.

How to Store and Dispose of This Medicine:

  • Store your new, unused medicine pen in the refrigerator, in the original carton, and protect it from light. Do not freeze this medicine, and do not use the medicine if it has been frozen. You may store the opened medicine pen in the refrigerator or at room temperature for 30 days. Throw away any unused medicine after 30 days.
  • Remove the needle from the pen before storing the medicine. This prevents leaking of the remaining medicine and prevents air bubbles from forming in the pen.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using diabetes medicines that you take by mouth such as chlorpropamide, glimepiride, glipizide, glyburide, tolbutamide, Diabeta®, Glucotrol®, or Orinase®.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, gallstones, an infection, or a history of pancreas problems. Tell your doctor if you have gastroparesis, which causes your stomach to empty more slowly than usual. Tell your doctor if you are dehydrated or have diarrhea, nausea, or vomiting. Tell your doctor if you have a history of angioedema (swelling of the arms, face, hands, mouth, or throat).
  • Check with your doctor right away if you develop a mass in the neck, difficulty swallowing, hoarseness, shortness of breath, trouble breathing, or wheezing. These may be symptoms of a serious thyroid problem.
  • Pancreatitis may occur while you are using this medicine. Tell your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • This medicine is only part of a program for controlling diabetes. You also must follow your doctor's instructions about diet, exercise, and checking your blood sugar.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or slurred speech
  • Change in how much or how often you urinate, or painful or burning urination
  • Difficulty swallowing
  • Fast heartbeat, increased hunger, or shakiness
  • Fever, chills, cough, sore throat, and body aches
  • Shortness of breath or trouble breathing
  • Sudden and severe stomach pain, nausea, vomiting, fever, and lightheadedness
  • Unusual tiredness or weakness

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, constipation, or upset stomach
  • Dizziness or headache
  • Redness, itching, swelling, or any changes in your skin where the shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/4/2014
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