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Japanese encephalitis virus vaccine, inactivated adsorbed (Injection)

Japanese Encephalitis Virus Vaccine, Inactivated Adsorbed (jap-a-NEEZ en-sef-a-LYTE-is VYE-rus VAX-een, in-AK-ti-vay-ted ad-SORBD)

Prevents Japanese encephalitis (brain swelling). This is a vaccine.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this vaccine if you have had an allergic reaction to Japanese encephalitis virus vaccine or protamine sulfate.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other health provider will give you this medicine.
  • This vaccine is given in 2 doses, 28 days apart. It is very important that you receive the second dose of the vaccine at least 7 days before you travel out of the country.
  • Tell your doctor if it has been more than 1 year since you received the second dose of the vaccine series, and you plan to travel outside of the country. You may need a booster dose before you leave.
  • This vaccine comes with a patient information sheet. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

If a dose is missed:

  • If you miss your appointment for the second shot, call your doctor to make another appointment as soon as possible.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you have a weakened immune system, or if you are using medicine that weakens your immune system, such as a steroid or cancer treatment.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have bleeding problems, low platelets in your blood, a weakened immune system, or an illness with a high fever (greater than 100°F).
  • Ixiaro® may not protect everyone who receives the vaccine.
  • Prevent mosquito bites by using insect repellent, protective clothing, and mosquito nets when you are outside.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast heartbeat
  • Fever
  • Flu-like symptoms

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, nausea, vomiting, loss of appetite
  • Headache
  • Irritability
  • Muscle pain
  • Redness, pain, or swelling where the shot was given
  • Vomiting (more common in children)

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 3/28/2016
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

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