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Fenofibric acid (By mouth)

Fenofibric Acid (fen-oh-FYE-brik AS-id)

Lowers high cholesterol and triglyceride levels in the blood.

Brand Name(s):

Fibricor, Trilipix

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to fenofibric acid, choline fenofibrate, or fenofibrate. Do not use this medicine if you are breastfeeding or if you have severe kidney disease (including patients receiving dialysis), liver disease, or a history of gallbladder disease.

How to Use This Medicine:

Delayed Release Capsule, Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Swallow the delayed-release capsule whole. Do not crush, break, or chew it.
  • Carefully follow your doctor's instructions about diet and exercise. This medicine is part of a complete plan for lowering cholesterol and triglycerides in your blood.
  • If you also use a medicine called a statin, you may use fenofibric acid and the statin at the same time each day.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you also use colchicine (Colcrys®), cyclosporine (Gengraf®, Neoral®, Sandimmune®), tacrolimus (Prograf®), other medicine to lower cholesterol (such as atorvastatin, pravastatin, simvastatin, Crestor®, Lipitor®, Vytorin®), or a blood thinner (such as acenocoumarol, dicumarol, warfarin, Coumadin®, Jantoven®). Tell your doctor if you drink alcohol regularly.
  • Tell your doctor if you also use cholestyramine (Questran®), colestipol (Colestid®), or colesevelam (Welchol®). You must take this medicine at least 1 hour before or 4 to 6 hours after you take any of these other medicines.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or if you have kidney disease, blood clotting problems, diabetes, heart disease, thyroid problems, or a history of muscle pain or weakness.
  • Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness. These could be symptoms of a serious muscle problem called myopathy.
  • Check with your doctor right away if you have dark-colored urine, fever, muscle cramps or spasms, muscle pain or stiffness, or unusual tiredness or weakness. These could be symptoms of a serious muscle problem called rhabdomyolysis, which can cause kidney problems.
  • Call your doctor right away if you have stomach pain with nausea and vomiting. This medicine may increase your risk of gallstones.
  • Tell your doctor right away if you have severe and sudden stomach pain, nausea, vomiting, fever, or lightheadedness. These may be symptoms of pancreatitis.
  • This medicine may lower the number of some types of blood cells in your body. If this happens, you may bleed or get infections more easily. Call your doctor if you have a fever, chills, or unusual bruising or bleeding.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Dark-colored urine or pale stools, yellow skin or eyes
  • Fever
  • Muscle pain, tenderness, or weakness
  • Sudden and severe stomach pain, nausea, vomiting, and lightheadedness
  • Unusual bleeding, bruising, or tiredness

If you notice these less serious side effects, talk with your doctor:

  • Back pain
  • Diarrhea
  • Headache
  • Mild skin rash
  • Stuffy or runny nose, chills, cough, sore throat, and body aches

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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