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Maraviroc (By mouth)

Maraviroc (mar-a-VIR-ok)

Treats human immunodeficiency virus (HIV) infection. HIV causes acquired immune deficiency syndrome (AIDS). This medicine does not cure HIV or AIDS, but combinations of drugs that treat HIV infection may slow the progress of the disease. This medicine is usually given to patients who have received HIV treatment in the past.

Brand Name(s):

Selzentry

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to maraviroc, or if you have severe kidney disease and are taking certain other medicines.

How to Use This Medicine:

Tablet

  • Take your medicine as directed.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Swallow the tablet whole. Do not crush, break, or chew it.
  • Maraviroc is used with other medicines to treat HIV infection. Make sure you take all of the medicines your doctor ordered. Do not stop taking this medicine, even for a short time, unless your doctor tells you to.
  • This medicine works best if there is a constant amount in the blood. To keep blood levels constant, take this medicine at the same time each day and do not miss any doses. Refill your prescription on time so you do not run out of medicine.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If your next regular dose is less than 6 hours away, wait until then to use the medicine and skip the missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using St John's wort, clarithromycin (Biaxin®), itraconazole (Sporanox®), ketoconazole (Nizoral®), nefazodone (Serzone®), rifampin (Rifadin®, Rimactane®), telithromycin (Ketek®), medicine to treat seizures (such as carbamazepine, phenobarbital, phenytoin, Dilantin®, Tegretol®), or other medicine to treat HIV or AIDS (such as atazanavir, darunavir, delavirdine, didanosine, efavirenz, enfuvirtide, etravirine, fosamprenavir, indinavir, lamivudine, lopinavir/ritonavir, nelfinavir, nevirapine, raltegravir, ritonavir, saquinavir, stavudine, tenofovir, tipranavir/ritonavir, zidovudine, Atripla®, Combivir®, Crixivan®, Emtriva®, Epzicom®, Intelence®, Invirase®, Kaletra®, Norvir®, Lexiva®, Prezista®, Rescriptor®, Reyataz®, Sustiva®, Trizivir®, Truvada®, Viracept®, Viread®).
  • Make sure your doctor knows if you are also using medicine to lower blood pressure. Some blood pressure medicines are amlodipine, atenolol, clonidine, hydrochlorothiazide, lisinopril, metoprolol, Benicar®, Cozaar®, Diovan®.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant, or if you have kidney disease, liver disease (including hepatitis B or C), heart disease, or low blood pressure.
  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.
  • Your immune system may get stronger when you start taking HIV medicines. Tell your doctor right away if you notice any changes in your health. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia, herpes, or tuberculosis.
  • Call your doctor right away if you have a rash with fever, pain in the upper stomach, dark urine, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious and life-threatening liver problem. This liver problem sometimes starts with an allergic reaction.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
  • Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loose skin, red skin rash, sores or ulcers on the skin, or fever or chills.
  • This medicine may weaken your immune system and increase your risk of infection . Talk to your doctor if you have concerns about this risk.
  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Chest pain
  • Dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, yellow skin or eyes
  • Dizziness, lightheadedness, or faintness when getting up suddenly from a lying or sitting position
  • Joint or muscle pain
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Constipation, diarrhea, nausea, gas
  • Cough, runny or stuffy nose, sore throat, body aches
  • Mild skin rash

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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