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Lanreotide (Subcutaneous)

Lanreotide (lan-REE-oh-tide)

Treats acromegaly (a growth hormone disorder) in patients who cannot be treated with surgery or radiation.

Brand Name(s):

Somatuline Depot

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to lanreotide.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
  • A nurse or other health provider will give you this medicine.

If a dose is missed:

  • Call your doctor or pharmacist for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using bromocriptine (Parlodel®), cyclosporine (Gengraf®, Neoral®, or Sandimmune®), quinidine (Quinidex®), terfenadine (Seldane®), diabetes medicine (insulin or oral medicine such as glyburide, metformin, Actos®, Avandia®, or Glucotrol®), or certain blood pressure medicines (such as atenolol, metoprolol, propranolol, or Toprol®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, kidney disease, liver disease, diabetes, or thyroid problems.
  • Tell your doctor if you are allergic to rubber. The needle cover of the prefilled syringe contains natural dry rubber latex, which may cause an allergic reaction if you have a latex allergy.
  • This medicine may raise or lower your blood sugar level.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Increased thirst, hunger, or urination.
  • Severe stomach pain with nausea and vomiting.
  • Slow heartbeat.
  • Unusual bleeding or bruising.
  • Unusual tiredness or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Constipation, diarrhea, passing gas, or mild nausea, vomiting, or stomach pain.
  • Headache.
  • Joint pain.
  • Pain, itching, or a lump under your skin where the shot is given.
  • Weight loss.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 4/4/2014

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