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Ibandronate (Injection)

Ibandronate (eye-BAN-droe-nate)

Treats or prevents osteoporosis (weak bones).

Brand Name(s):

Boniva

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to ibandronate, or if you have very low calcium in the blood (hypocalcemia).

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. You might need to have a blood test done before you are given each dose.
  • A nurse or other health provider will give you this medicine.
  • This medicine is usually given every 3 months.
  • Follow your doctor's instructions if you need to take calcium and vitamin D supplements.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

If a dose is missed:

  • Call your doctor or pharmacist for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using medicine or receiving treatments that weaken your immune system, such as cancer treatment, radiation treatment, or steroids (such as dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone, Medrol®).
  • This medicine may interact with the dye used for bone scans.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease or other diseases that may affect your kidneys, such as diabetes, high blood pressure, or heart disease. Tell your doctor if you have a mineral or vitamin deficiency or imbalance or trouble absorbing minerals in your stomach (malabsorption syndrome).
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine could cause jaw problems, especially if you have a tooth pulled or have other dental work. Tell your doctor or dentist if you have pain, swelling, or other problems in your mouth or jaw. Make sure your doctor knows about dental problems that you already have and if you wear dentures. Also tell your doctor if you have cancer, anemia, or blood clotting problems, because you could be more likely to develop jaw problems.
  • This medicine could lower the amount of calcium in your blood. Call your doctor right away if you develop any signs of low calcium levels, such as muscle spasms or twitching, or numbness or tingling in your fingers, toes, or lips.
  • This medicine may increase your risk of breaking a thigh bone. This may be more common if you use it for a long time. Check with your doctor right away if you have dull or aching pain in the thigh, groin, or hips.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blood in the urine, lower back pain, side pain, or sharp back pain just below the ribs
  • Change in how much or how often you urinate, difficult or painful urination
  • Heavy feeling in the jaw, loose teeth, or other teeth problems
  • Pain, swelling, or numbness in the mouth or jaw
  • Muscle spasms, twitching, tingling, numbness
  • Severe bone, muscle, joint, or back pain
  • Unusual pain in your thigh, groin, or hip

If you notice these less serious side effects, talk with your doctor:

  • Back or joint pain
  • Fever, chills, cough, stuffy or runny nose, sore throat, and body aches (within 3 days)
  • Pain, itching, burning, swelling, or a lump under your skin where the needle was placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014
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