Isosorbide dinitrate/hydralazine (By mouth)
Hydralazine Hydrochloride (hye-DRAL-a-zeen hye-droe-KLOR-ide), Isosorbide Dinitrate (eye-soe-SOR-bide dye-NYE-trate)
Treats heart failure.
BiDilThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to nitrates, isosorbide, or hydralazine.
How to Use This Medicine:
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some medicines can affect how isosorbide dinitrate/hydralazine works. Tell your doctor if you are using any of the following:
- Blood pressure medicine or a beta blocker, such as lisinopril, metoprolol, or propranolol
- Medicine to treat erectile dysfunction, such as sildenafil, tadalafil, or vardenafil
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have low blood pressure, cardiomyopathy, or you had a heart attack.
- This medicine may cause the following problems:
- Symptoms of lupus (may go away when you stop using the medicine)
- Worsening heart disease
- This medicine could cause you to feel dizzy or lightheaded. This is more likely to happen if you are dehydrated. Drink plenty of fluids to help prevent dehydration. Stand up slowly to help prevent dizziness.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain or pressure
- Fast or pounding heartbeat
- Joint pain, fever, an overall ill feeling
- Lightheadedness or fainting
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
If you notice these less serious side effects, talk with your doctor:
- Feeling very tired or weak
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 11/4/2014
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