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Dexchlorpheniramine maleate (By mouth)

Dexchlorpheniramine Maleate (dex-klor-fen-IR-a-meen MAL-ee-ate)

Treats sneezing, runny or stuffy nose, watery eyes, and other symptoms of seasonal allergies. Also treats skin hives and swelling caused by allergic reactions.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to dexchlorpheniramine. You should not use this medicine if you are using an MAO inhibitor such as Eldepryl®, Marplan®, Nardil®, Parnate®, or a blood thinner such as warfarin (Coumadin®). Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years old. Using these medicines in very young children might cause serious or possibly life-threatening side effects.

How to Use This Medicine:

Long Acting Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Swallow the extended-release tablet whole. Do not crush, break, or chew it. It is best to use this medicine at bedtime.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have any allergies.
  • Make sure your doctor knows if you have a blocked digestive tube, diabetes, glaucoma, heart disease, high blood pressure, problems with urination due to enlarged prostate, blocked bladder, stomach ulcer, or thyroid disease.
  • Make sure your doctor knows if you have breathing problems such as asthma, chronic bronchitis, or emphysema. Tell your doctor if you have a cough caused by smoking, or breathing problems.
  • This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision.
  • Change in how much or how often you urinate.
  • Dizziness, confusion, or agitation.
  • Fast, irregular, or pounding heartbeat.
  • Fever.
  • Lightheadedness or fainting.
  • Numbness, tingling, or burning pain in your hands, arm, legs, or feet.
  • Pale skin or pale lip color.
  • Seizure.
  • Trouble breathing, wheezing, or cough with mucus.
  • Unusual bleeding, bruising, or weakness.

If you notice these less serious side effects, talk with your doctor:

  • Confusion, feeling restless or excited.
  • Changes in your menstrual period.
  • Mild skin rash, itching, or redness.
  • Mild nausea, vomiting, constipation, diarrhea, loss of appetite, or stomach pain.
  • Ringing in your ears, headache.
  • Stuffy nose, dry mouth, nose, or throat.
  • Trouble sleeping or weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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