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Sufentanil (Injection)

Sufentanil (soo-FEN-ta-nil)

Treats pain. This medicine may be used along with anesthetic medicine during surgery or during childbirth.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to sufentanil or certain other narcotic pain medicines.

How to Use This Medicine:


  • A nurse or other health provider will give you this medicine.
  • Your doctor will prescribe your exact dose. This medicine is given through a needle placed in one of your veins or into your back (spinal cord).

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
  • Make sure your doctor knows if are using a blood thinner such as warfarin (Coumadin®).
  • Make sure your doctor knows if you are using heart or blood pressure medicine such as beta blockers (atenolol, metoprolol, propranolol, Inderal®, or Toprol®) or calcium channel blockers (such as diltiazem, nifedipine, verapamil, Lotrel®, Norvasc®, Tiazac®).
  • There are many other drugs that can interact with sufentanil. Make sure your doctor knows about all other medicines you are using.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding.
  • Make sure your doctor knows if you have breathing problems, liver disease, or kidney disease. Tell your doctor if you have bleeding problems or an infection where the needle is to be placed.
  • Make sure your doctor knows if you have ever had a serious head injury, or any medical problem that causes increased pressure in your head.
  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, shortness of breath.
  • Decrease in how much or how often you urinate.
  • Fast, slow, or uneven heartbeat.
  • Lightheadedness or fainting.
  • Muscle stiffness.
  • Numbness or weakness in your arm, leg, or on one side of your body.

If you notice these less serious side effects, talk with your doctor:

  • Chills.
  • Drowsiness.
  • Mild skin rash or itching.
  • Nausea or vomiting.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 3/28/2016
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