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Perflutren protein type A microsphere (Injection)

Perflutren Protein Type A Microsphere (per-FLOO-tren PROE-teen type A MYE-kroe-sfeers)

Used during a heart procedure called a 2D ECHO (echocardiography). Helps your doctor see the inside of your heart more clearly. Perflutren protein type A microsphere is no longer available in the United States.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to perflutren protein type A microsphere, blood, blood products, or albumin. You should not receive this medicine if you have unstable angina, unstable or worsening congestive heart failure, heart rhythm problems (such as QT prolongation), or have recently had a heart attack. You should not receive this medicine if you have serious breathing problems or lung disease, such as severe emphysema or blood clots in the lungs.

How to Use This Medicine:


  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have serious liver disease, any heart defects, or a heart or lung condition that has recently gotten worse.
  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made of human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during manufacture of these medicines. Although the risk is low, talk with your doctor if you have concerns.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision.
  • Chest pain or fast heartbeat.
  • Fever or chills.
  • Trouble with breathing.

If you notice these less serious side effects, talk with your doctor:

  • Change in taste.
  • Dizziness or headache.
  • Dry mouth, nausea, or vomiting.
  • Redness, pain, itching, or rash where the needle is placed.
  • Warmth or redness in your face, neck, arms, or upper chest.
  • Weakness or muscle cramps.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 4/4/2014

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