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Nalmefene (Injection)

Nalmefene (NAL-me-feen)

Helps reverse the effects of certain opioid (narcotic) medicines. The manufacturer stopped making this medicine on June 30, 2008.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to nalmefene.

How to Use This Medicine:

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
  • A nurse or other trained health professional will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using flumazenil.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, liver disease, or kidney disease.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Diarrhea or severe stomach pain.
  • Dizziness, drowsiness, or confusion.
  • Fast or uneven heartbeat.
  • Fever, chills, or sore throat.
  • Lightheadedness or fainting.
  • Twitching or muscle cramps.

If you notice these less serious side effects, talk with your doctor:

  • Anxiety or depression.
  • Dry mouth, nausea, or vomiting.
  • Headache or joint pains.
  • Increased sweating.

Last Updated: 6/12/2013

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