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Enalaprilat (Injection)

Enalaprilat (en-AL-a-pril-at)

Treats high blood pressure (hypertension). This medicine is an ACE inhibitor.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to enalaprilat or to any ACE inhibitors such as Accupril®, Altace®, or Lotensin®. You should not use this medicine if you have a condition called hereditary angioedema. You should not use this medicine if you are pregnant.

How to Use This Medicine:


  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using diuretics ("water pills") such as amiloride, hydrochlorothiazide (HCTZ), furosemide, torsemide, Demadex®, Lasix®, spironolactone, triamterene, or Aldactone®.
  • Tell your doctor if you are using pain or arthritis medicine (sometimes called "NSAIDs") such as aspirin, diclofenac, ibuprofen, etodolac, indomethacin, piroxicam, naproxen, Advil®, Aleve®, Celebrex®, Feldene®, Indocin®, Relafen®, Motrin®, or Voltaren®.
  • Let your doctor know if you are using lithium, potassium supplements, or salt substitutes that contain potassium.
  • Make sure your doctor knows if you have ever been given a medicine to make you less sensitive to bee or ant stings.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Make sure your doctor knows if you are breast feeding.
  • Make sure your doctor knows if you have diabetes, heart disease, kidney disease, or if you are on dialysis.
  • Tell your doctor if you have a collagen vascular disease such as lupus or arthritis.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling red skin rash, itching, or loss of hair.
  • Chest pain, uneven heartbeat, fast or slow heartbeat.
  • Decrease in how much or how often you urinate.
  • Lightheadedness or fainting.
  • Numbness or tingling in your hands, arms, legs, or feet, or muscle cramps.
  • Problems with walking or dizziness.
  • Trouble breathing or catching your breath.
  • Yellowing of your skin or the whites of your eyes.
  • Unusual bleeding, bruising, weakness, coughing up blood, or bloody, black tarry stools.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision, redness or watering of eyes, ringing in your ears, or loss of smell.
  • Burning pain while urinating.
  • Change in taste.
  • Cough, sore throat, or runny nose.
  • Depression, confusion, or headache.
  • Fever, fatigue, drowsiness, or lack of sleep.
  • Nausea, vomiting, constipation, thirst, or dry mouth.
  • Sweating, warmth, or redness in your chest, neck, or face.
  • Trouble having sex or increase in the size of breasts in men.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/4/2014
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