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Caspofungin (Intravenous)

Caspofungin (kas-poe-FUN-jin)

Treats infections caused by a fungus such as Candida or Aspergillosis. Also used to treat fungus infections in patients who are unable to use other medicines (such as amphotericin B or itraconazole).

Brand Name(s):

Cancidas

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You or your child should not receive this medicine if you have had an allergic reaction to caspofungin.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • This medicine must be given slowly, so the needle will remain in place for about 1 hour.
  • In most cases, this medicine is given for at least 2 weeks, but may be continued for longer. Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you or your child is using carbamazepine (Tegretol®), cyclosporine (Gengraf®, Neoral®, Sandimmune®), dexamethasone (Decadron®), efavirenz (Sustiva®), nevirapine (Viramune®), phenytoin (Dilantin®), rifampin (Rifadin®, Rifater®, Rimactane®), or tacrolimus (Prograf®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you or your child has liver disease.
  • Check with your doctor right away if you or your child have any symptoms of liver problems including dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, or yellowing of your skin or the whites of your eyes.
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after receiving this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Decrease in how much or how often you urinate.
  • Dry mouth, increased thirst, or muscle cramps.
  • Fast or slow heartbeat.
  • Fever, cough, sore throat, and body aches.
  • Lightheadedness or fainting.
  • Swelling in your hands, ankles, or feet.
  • Tremors, shaking, or sweating.
  • Trouble breathing or breathing too fast.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Headache.
  • Mild skin rash.
  • Nausea, vomiting, diarrhea, or pain in your upper stomach.
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.
  • Trouble sleeping.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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