Skip to main content

Risperidone (Injection)

Risperidone (ris-PER-i-done)

Treats schizophrenia and certain problems caused by bipolar disorder.

Brand Name(s):

Risperdal Consta

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to risperidone.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • A nurse or other health provider will give you this medicine. This medicine is usually given every 2 weeks.

If a dose is missed:

  • You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • There are many other medicines that you should not use while you are taking risperidone. Taking risperidone with certain other medicines may be dangerous, even life-threatening. Make sure your doctor and your pharmacist knows about all other medicines you are using.
  • Make sure your doctor knows if you are taking carbamazepine (Tegretol®), cimetidine (Tagamet®), furosemide (Lasix®), levodopa (Larodopa®), fluoxetine (Prozac®), paroxetine (Paxil®), phenobarbital (Luminal®), ranitidine (Zantac®), or valproate (Depakene®, Depakote®). Tell your doctor if you are using clozapine (Clozaril®), quinidine, phenytoin (Dilantin®), or rifampin (Rifadin®). Make sure your doctor knows if you are also using medicine to lower blood pressure (such as atenolol, hydrochlorothiazide (HCTZ), lisinopril, metoprolol, quinapril, Accupril®, Cozaar®, Diovan®, Lotrel®, Norvasc®, Toprol®, or Zestril®).
  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or if you plan to become pregnant while you are using this medicine, or during the 12 weeks after you stop using it. Do not breastfeed while you are using this medicine and for at least 12 weeks after you receive the last shot.
  • Make sure your doctor knows if you have kidney disease, liver disease, diabetes, breast cancer, bone problems, brain tumor, bowel blockage, Reye's syndrome, Parkinson's disease, trouble with swallowing, or a history of seizures or neuroleptic malignant syndrome (NMS). Tell your doctor if you have any kind of blood vessel or heart problems, including low blood pressure, heart failure, a low amount of blood, heart rhythm problems, or a history of a heart attack or stroke.
  • This medicine may cause an increase in your blood sugar. If you have diabetes, you may need to check your blood sugar more often. If you are using a medicine for diabetes, your doctor may need to change your dose.
  • This medicine is not approved to treat behavior disorders in older people who have dementia. Using this medicine to treat this problem could increase the risk of death. This risk has not been shown for the approved uses of this medicine.
  • Some side effects are more likely to happen in elderly people who have memory problems or other reduced mental skills. Make sure the doctor knows if the person who will be using this medicine has forgetfulness or confusion related to aging (such as Alzheimer's disease or dementia).
  • Stop taking this medicine and check with your doctor right away if you have any of the following symptoms while using this medicine: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).
  • Tardive dyskinesia (a movement disorder) may occur and may not go away after you stop using the medicine. Check with your doctor right away if you have any of the following symptoms while taking this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.
  • This medicine may make you dizzy, lightheaded, or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert. Change positions slowly when getting up from a lying or sitting position.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Avoid people who are ill, and wash your hands often. Brush and floss your teeth gently, do not play rough sports, and be careful with sharp objects.
  • This medicine might reduce how much you sweat. Your body could get too hot if you do not sweat enough. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might vomit or have an upset stomach. Do not get too hot while you are exercising. Avoid places that are very hot. Call your doctor if you are too hot and cannot cool down.
  • This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these adverse effects, tell your doctor right away.
  • This medicine may increase your weight. Your doctor may need to check your weight regularly during treatment with this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate.
  • Chills, cough, sore throat, and body aches.
  • Dry mouth, increased hunger or thirst, or muscle cramps.
  • Fast, slow, pounding, or uneven heartbeat.
  • Feeling depressed, agitated, or nervous.
  • Fever, sweating, confusion, or muscle stiffness.
  • Lightheadedness, dizziness, or fainting.
  • Mood or behavioral changes, or thoughts of hurting yourself or others.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Painful, prolonged erection of your penis (in males).
  • Problems with balance or walking.
  • Seizures or tremors.
  • Swelling in your hands, ankles, or feet.
  • Trouble with speaking or swallowing.
  • Twitching or muscle movements you cannot control (often in your eyes, jaw, neck or upper body).
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision or change in vision.
  • Constipation, diarrhea, nausea, vomiting, or stomach pain or upset.
  • Dry mouth or drooling.
  • Headache.
  • Pain, swelling, or a lump under your skin where the shot is given.
  • Rash or itching skin.
  • Stuffy or runny nose.
  • Weight gain.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

Copyright © 1984- Thomson Micromedex. All rights reserved.

Thomson & A.D.A.M