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Vasopressin (Injection)

Vasopressin (vay-soe-PRES-in)

Keeps your body from losing too much water. Used after abdominal surgery or before abdominal x-rays. Also treats Diabetes Insipidus ("water diabetes"). This medicine is a hormone.

Brand Name(s):

Novaplus Vasopressin, Pitressin

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medication if you have had an allergic reaction to vasopressin.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin or into one of your muscles.
  • You may be told to drink a certain amount of liquid each day while you are using this medicine. Follow these instructions carefully.

How to Store and Dispose of This Medicine:

  • If you store this medicine at home, keep it at room temperature, away from heat and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using carbamazepine (Tegretol®), fludrocortisone (Florinef®), demeclocycline (Declomycin®), lithium (Eskalith®), medicine for depression (such as amitriptyline, nortriptyline, Norpramin®, Vivactil®), chlorpropamide (Diabinese®), clofibrate (Abitrate®), mecamylamine, trimethaphan, urea (Ureaphil®), or heparin.
  • Tell your doctor if you drink alcohol.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have heart disease, blood vessel disease, seizures, migraine headaches, asthma, or kidney disease.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest, neck, or jaw pain or tightness.
  • Unusual tiredness, sleepiness, and headache.

If you notice these less serious side effects, talk with your doctor:

  • Mild stomach pain, nausea, or gas.
  • Pale skin.
  • Sweating more than usual.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/4/2014
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