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Doxorubicin hydrochloride liposome (Injection)

Doxorubicin Hydrochloride Liposome (dox-oh-ROO-bi-sin hye-droe-KLOR-ide LYE-poh-some)

Treats cancer, including ovarian cancer, multiple myeloma, and Kaposi sarcoma.

Brand Name(s):

Doxil, Lipodox, Lipodox 50

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to doxorubicin or if you are pregnant.

How to Use This Medicine:

Injectable

  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have liver disease, congestive heart failure, or heart or blood vessel disease. Tell your doctor if you have received previous chemotherapy or radiation treatment.
  • This medicine may cause the following problems:
    • Heart damage
    • Hand-foot syndrome
    • Cancer of the mouth
    • Infusion reactions
  • Your urine color may change to red or orange after you receive the injection. This is normal.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, redness, numbness, pain, or swelling of the palms, hands, and bottoms of the feet
  • Fever, chills, cough, sore throat, and body aches
  • Painful sores or white patches on your lips, mouth, or throat
  • Rapid weight gain, swelling in your hands, ankles, or feet, uneven heartbeat
  • Redness, swelling, burning, or pain where the needle is placed
  • Unusual bleeding, bruising, or weakness
  • Warmth or redness in your face, neck, arms, or upper chest, shortness of breath, headache, chills, dizziness

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, constipation, nausea, vomiting, loss of appetite
  • Hair loss
  • Reddish-orange urine or other body fluids

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014
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