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Cisplatin (Injection)

Cisplatin (sis-PLA-tin)

Treats cancer of the testicles, bladder, ovaries, or lung.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to cisplatin or to anything that contains platinum. Do not use it if you are pregnant or have kidney problems, hearing loss, or blood or bone marrow problems.

How to Use This Medicine:

Injectable

  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • Drink extra fluids so you will urinate more often and help prevent kidney problems.
  • Tell your caregiver right away if this medicine gets on your skin or in your eyes, nose, or mouth.
  • Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how cisplatin works. Tell your doctor if you are taking seizure medicine or if you have ever been treated with radiation or other cancer drugs.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding or have any health conditions.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • Your doctor will need to check your blood and urine at regular visits while you are using this medicine. You may also need to have hearing tests. Keep all appointments.
  • Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
  • Side effects may appear in between treatments or after you have stopped using this medicine.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate
  • Confusion, weakness, and muscle twitching
  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
  • Fever, chills, sore throat, cough
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Ringing, buzzing, or trouble hearing in one or both ears
  • Uncontrollable nausea and vomiting
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea, loss of appetite
  • Pain, redness, or swelling where the IV needle is inserted

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 11/4/2014
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