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Clonidine (Absorbed through the skin)

Clonidine (KLOE-ni-deen)

Treats high blood pressure. A lower blood pressure will reduce the risk of strokes and heart attacks. May be used alone or together with other medicines. Belongs to a class of drugs called antihypertensives.

Brand Name(s):

Catapres TTS-3, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to clonidine.

How to Use This Medicine:

Patch

  • Your doctor will tell you how many patches to use, where to apply them, and how often to apply them. Do not use more patches or apply them more often than your doctor tells you to.
  • The patch should be left on your skin for 7 days. Follow your doctor's instructions carefully. Do not remove the patch without your doctor's approval. Even if you feel fine, your blood pressure can still be high.
  • Wash your hands with soap and water before and after applying a patch.
  • Leave the patch in its sealed wrapper until you are ready to put it on. Tear the wrapper open carefully. NEVER CUT the wrapper or the patch with scissors. Do not use any patch that has been cut by accident.
  • The patient instructions will show the body areas where you can wear the patch. When putting on each new patch, choose a different place within these areas. Do not put the new patch on the same place you wore the last one. Be sure to remove the old patch before applying a new one.
  • Apply the patch to clean, dry skin that has very little hair or no hair. Do not put the patch over burns, cuts, or irritated skin.
  • Put on a new patch if the old one has fallen off and cannot be reapplied.
  • Leave the patch in place even when you shower, bathe, or swim. If the patch loosens, cover it with an extra adhesive overlay that is provided in the box.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

If a dose is missed:

  • If you forget to wear or change a patch, put one on as soon as you can. If it is almost time to put on your next patch, wait until then to apply a new patch and skip the one you missed. Do not apply extra patches to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.
  • Fold the used patch in half with the sticky sides together. Throw any used patch away so that children or pets cannot get to it. You will also need to throw away old patches after the expiration date has passed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you use digoxin (Digitek®, Lanoxin®), other blood pressure medicines (such as amlodipine, atenolol, diltiazem, metoprolol, propranolol, verapamil, Bystolic®, Caduet®, Lotrel®, Tenormin®), medicines to treat depression (such as amitriptyline, nortriptyline, Elavil®), or medicine to treat mental illness (such as haloperidol, promethazine, Phenergan®, Thorazine®).
  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding or if you have kidney disease, heart or blood vessel disease, heart rhythm problems, or a history of heart attack or stroke.
  • This medicine contains aluminum. Make sure you remove the patch before you have a magnetic resonance imaging (MRI) scan to prevent skin burns at the patch site.
  • This medicine may make you drowsy, dizzy, or lightheaded. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
  • Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine. Tell your doctor if you drink alcohol or use pain relievers or sleeping pills.
  • You may have some skin redness, a rash, itching, or blistering at the place where you wear the patch. If this irritation is severe or does not go away, call your doctor. Do not remove the patch unless your doctor tells you to.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine may cause dryness of the eyes. If you wear contact lenses, this may be a problem for you. Talk to your doctor and discuss how to treat the dryness.
  • Even if you feel well, do not stop using the medicine without asking your doctor. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, slow, pounding, or uneven heartbeat
  • Lightheadedness, dizziness, drowsiness, or fainting
  • Skin rash, blistering, swelling, or redness where the patch is worn
  • Unusual tiredness or weakness

If you notice these less serious side effects, talk with your doctor:

  • Dry eyes, mouth, or throat
  • Headache
  • Mild skin rash

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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