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Carisoprodol/aspirin (By mouth)

Aspirin (AS-pir-in), Carisoprodol (kar-eye-soe-PROE-dol)

Treats muscle spasms, pain, and stiffness. This medicine is a combination of a muscle relaxant and a nonsteroidal anti-inflammatory medicine (NSAID).

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction (including asthma) to carisoprodol, meprobamate (Miltown®, Equagesic®), or aspirin. You should not use this medicine if you have a history of bleeding disorders, porphyria (an enzyme problem), stomach or bowel problems (such as blockage, bleeding), or active stomach ulcers. You should not use this medicine if you are pregnant or breastfeeding. This compound should not be given to children or teenagers with fever or flu symptoms unless approved by a doctor.

How to Use This Medicine:

Tablet

  • Take your medicine as directed.
  • It is best to take this medicine with food or milk.
  • This medicine is not for long-term use. This medicine should only be used for 2 to 3 weeks.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using St. John's wort, fluvoxamine (Luvox®), omeprazole (Prilosec®), or rifampin (Rifadin®, Rimactane®). Tell your doctor if you are also using medicine to lower blood pressure (such as atenolol, enalapril, hydrochlorothiazide [HCTZ], lisinopril, metoprolol, quinapril, Accupril®, Cozaar®, Diovan®, Lotrel®, Toprol®, or Zestril®), pain or arthritis medicine called "NSAID" (such as ibuprofen, Aleve®, Celebrex®, or Motrin®), insulin, or diabetes medicine that you take by mouth (such as glipizide, glyburide, tolbutamide, or Glucotrol®).
  • Make sure your doctor knows if you are also using acetazolamide (Diamox®), methotrexate (Folex®, Rheumatrex®), blood thinners (such as clopidogrel, heparin, warfarin, or Coumadin®), a steroid medicine (such as dexamethasone, prednisolone, prednisone, or Medrol®), or an MAO inhibitors (MAOI) such as Marplan®, Nardil®, or Parnate®.
  • Make sure your doctor knows if you are also using probenecid (Benemid®), sulfinpyrazone (Anturane®), or antacid or stomach medicine including ranitidine, sucralfate, Carafate®, Pepcid®, Tagamet®, or Zantac®.
  • Do not drink alcohol while you are using this medicine.
  • Tell your doctor if you drink alcohol or if you are using any medicine that makes you sleepy, such as allergy medicine or narcotic pain medicine.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Make sure your doctor knows if you have kidney disease, liver disease, or seizures. Tell your doctor if you have a history of drug abuse or dependence.
  • This medicine can cause dizziness or drowsiness. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • To avoid dizziness from this medicine, stand up slowly from a lying or sitting position.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine may cause bleeding in your stomach or intestines. This problem can happen without warning signs. This is more likely if you have had a stomach ulcer in the past, if you drink alcohol regularly, if you are over 60 years of age, are in poor health, or are using certain other medicines (such as a blood thinner or nonsteroidal anti-inflammatory medicine [NSAIDs]).
  • This medicine may also cause a serious type of allergic reaction called anaphylaxis. Although this is rare, it may occur more often in patients who are allergic to aspirin or to any of the nonsteroidal anti-inflammatory drugs. Anaphylaxis can be life-threatening and requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face; very fast but irregular heartbeat or pulse; hive-like swellings on the skin; and puffiness or swellings of the eyelids or around the eyes. If these effects occur, get emergency help at once.
  • Call your doctor if your symptoms do not improve or if they get worse. Do not use the medicine for more than 2 to 3 weeks (14 to 21 days) to treat pain unless your doctor has told you to.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blood in your urine.
  • Bloody or black, tarry stools.
  • Fast, pounding, or uneven heartbeat.
  • Fever, chills, cough, sore throat, and body aches.
  • Ringing in the ears.
  • Seizures.
  • Severe drowsiness.
  • Skin rash, hives, itching, or swelling.
  • Slow heartbeat.
  • Trouble breathing.
  • Vomiting blood or something that looks like coffee grounds.
  • Weight loss.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Headache.
  • Nausea, vomiting, loss of appetite, heartburn, or stomach pain or cramps.
  • Restlessness or irritability.
  • Skin rash or itching.
  • Trouble sleeping.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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