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Ranitidine (By mouth)

Ranitidine Hydrochloride (ra-NI-ti-deen hye-droe-KLOR-ide)

Treats and prevents heartburn with acid indigestion. Also treats stomach ulcers, gastroesophageal reflux disease (GERD), and conditions that cause your stomach to make too much acid (such as Zollinger-Ellison syndrome). This medicine is a histamine H2-blocker.

Brand Name(s):

FusePaq Deprizine, Gabitidine, Good Neighbor Pharmacy Acid Control 150, Good Sense Acid Reducer, Leader Acid Control, Leader Ranitidine HCl, Rite Aid Acid Reducer, Sentradine, The Medicine Shoppe Acid Reducer, TopCare Heartburn Relief 150, TopCare Heartburn Relief 75, Zantac, Zantac 150, Zantac 300, Zantac 75

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to ranitidine or similar medicines such as cimetidine (Tagamet®) or nizatidine (Axid®).

How to Use This Medicine:

Capsule, Tablet, Liquid, Fizzy Tablet, Liquid Filled Capsule, Granule

  • Take your medicine as directed.
  • Follow the instructions on the medicine label if you are using this medicine without a prescription.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Swallow the tablet with a full glass of water.
  • The effervescent tablet should not be chewed, swallowed whole, or dissolved on the tongue. The Zantac 25 EFFERdose Tablet should be mixed in 1 teaspoonful (or more) of water. The Zantac 150 EFFERdose Tablet should be mixed in 6 to 8 ounces (about 1 cup) of water. Do not drink the liquid until the tablet is completely dissolved.
  • If you are using this medicine to prevent heartburn, take it 30 to 60 minutes before eating or drinking anything that causes you to have heartburn.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You may store the oral liquid in the refrigerator.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using triazolam (Halcion®), or a blood thinner such as warfarin (Coumadin®).

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding. Tell your doctor if you have kidney disease, liver disease, or a history of acute porphyria.
  • Before using this medicine, tell your doctor if you have had heartburn for longer than 3 months, if you have trouble swallowing food, if you are vomiting blood, or have blood in your stools. These may be signs of a more serious stomach condition.
  • Heartburn pain that causes you to sweat, become lightheaded or dizzy, or have chest pain spreading to your arms or shoulders may be an indication of a heart attack. Seek emergency medical help if you have any of these symptoms.
  • EFFERdose® tablets contain phenylalanine. If you have phenylketonuria (PKU), talk to your doctor before using this medicine.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash.
  • Dark-colored urine or pale stools.
  • Fast, slow, or uneven heartbeat.
  • Nausea, vomiting, loss of appetite, pain in your upper stomach.
  • Unusual bleeding, bruising, or weakness.
  • Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

  • Constipation or diarrhea.
  • Headache, may be severe.
  • Mild nausea, vomiting, or stomach pain.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 4/4/2014

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