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Clobetasol propionate (On the skin)

Clobetasol Propionate (kloe-BAY-ta-sol PROE-pee-oh-nate)

Treats skin problems such as psoriasis, skin irritation, and allergic reactions. This medicine is a corticosteroid.

Brand Name(s):

Clobex, Cormax Scalp Application, Embeline Scalp Application, Olux, Olux-E, Temovate, Temovate E

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not use this medicine if you have had an allergic reaction to clobetasol.

How to Use This Medicine:

Cream, Foam, Gel/Jelly, Liquid, Lotion, Ointment, Shampoo, Spray

  • Take your medicine as directed.
  • Use this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
  • Do not cover, wrap, or wear tight fitting clothes over your treated skin areas unless directed by your doctor. Allow the cream or liquid to dry before putting on your clothes.
  • Cream, shampoo, or spray: Do not use this medicine on your face, armpits, or groin area unless your doctor tells you to.
  • Shampoo: Apply the shampoo to your dry scalp. Part your hair so that you only treat the affected areas. Apply a small amount to the area, massage gently, and leave it on for 15 minutes. Add water, lather, and rinse well.
  • Wash your hands with soap and water before and after you use this medicine.Make sure your skin is clean and dry before you apply this medicine.
  • Apply a thin layer of the medicine to the affected area. Rub it in gently.
  • Do not inhale this medicine or use it near heat or an open flame. Do not puncture, break, or burn the aerosol can.
  • It is very important that you keep using this medicine for the full time of treatment to help clear up your skin or scalp problem completely . Do not miss any doses.
  • This medicine is not for long-term use.Do not use this medicine for more than 2 weeks at a time unless directed by your doctor. Tell your doctor if you skin condition does not improve within 2 weeks.

If a dose is missed:

  • Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not refrigerate or freeze.
  • Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • This medicine should not be used together with other corticosteroid medicines, such as betamethasone, hydrocortisone, triamcinolone, Cortaid®, or Lotrisone®, unless directed by your doctor.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, Cushing disease, diabetes, or a skin infection.
  • This medicine may increase your risk of adrenal gland problems. The risk is greater for children and patients who use large amounts of medicine or use it for a long time. Talk to your doctor about the symptoms you should watch for. Some possible symptoms are dizziness or lightheadedness, unusual tiredness or weakness, feeling cold, loss of appetite, puffy face, and thin skin that bruises easily.
  • Tell your doctor right away if your skin becomes very irritated, dry, red, or swollen or starts to itch or burn. These may be signs of an infection.
  • Do not use this medicine to treat a skin problem your doctor has not examined.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.Call your doctor if your skin problem is not better within 2 weeks.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Color changes on the skin, dark freckles, easy bruising, muscle weakness
  • Round, puffy face
  • Weight gain around your neck, upper back, breast, face, or waist
  • Burning, pain, redness, or thinning of the skin
  • Dizziness or lightheadedness
  • Fever, cough, runny nose, sore throat
  • Increase in thirst or how often you urinate

If you notice these less serious side effects, talk with your doctor:

  • Mild acne, pain, redness, swelling, or burning on the application site
  • Swollen hair pores, excess hair growth

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 4/4/2014

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