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Oxybutynin (By mouth)

Oxybutynin (ox-i-BUE-ti-nin)

Treats overactive bladder.

Brand Name(s):

Ditropan XL

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to oxybutynin, if you have narrow-angle glaucoma that is not under control, or if you have trouble or are not able to urinate. You should not use this medicine if you have trouble or are not able to pass food through your stomach (you often feel bloated or too full, or have frequent constipation).

How to Use This Medicine:

Liquid, Tablet, Long Acting Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • You may take this medicine with or without food.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Swallow the extended-release tablet whole. Do not crush, break, or chew it. Take this medicine with water or any liquids.
  • If you take the extended-release tablet, part of the tablet may pass into your stools. This is normal and is nothing to worry about.
  • Take this medicine at the same time each day.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze the oral liquid.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using a medicine that may irritate your stomach, or a medicine used to treat osteoporosis or other bone problems (such as alendronate, etidronate, risedronate, Actonel®, Didronel®, or Fosamax®). Tell your doctor if you are also using certain antibiotics (such as clarithromycin, erythromycin, Biaxin®, or Ery-Tab®) or medicine to treat a fungus infection (such as itraconazole, ketoconazole, miconazole, Nizoral®, or Sporanox®).
  • Tell your doctor if you are also using any other medicine to treat incontinence, or other medicine that can cause dry mouth or constipation (such as atropine, dicyclomine, glycopyrrolate, scopolamine, Bentyl®, Robinul®, or Transderm Scop®).
  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, bleeding problems, dementia (mental problem), glaucoma, trouble swallowing, myasthenia gravis (a disease causing muscle weakness), prostate problems, trouble emptying your bladder, or any kind of digestive problem (such as colitis, constipation, a blockage in your intestines, or gastroesophageal reflux disease [GERD]).
  • This medicine may cause a serious type of allergic reaction called angioedema. Angioedema may be life-threatening and requires immediate medical attention. Stop using this medicine and seek medical attention right away if you or your child have a rash; itching; a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs; trouble with breathing; or chest tightness while you are using this medicine.
  • Oxybutynin may cause agitation, confusion, sleepiness or unusual drowsiness, or hallucinations (seeing, hearing, or feeling things that are not there). These symptoms are more likely to occur when you begin taking this medicine, or when the dose is increased. If you or your child have these symptoms, stop using this medicine and tell your doctor right away.
  • This medicine may make you dizzy, drowsy, or have blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you or your child are not alert or not able to see well.
  • This medicine may make you or your child have trouble sweating and cause your body to get too hot. Use extra care to avoid becoming overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Agitation, confusion or extreme behavior changes, or unusual drowsiness.
  • Change in how much or how often you urinate.
  • Fast, pounding, or uneven heartbeat.
  • Fever or cough.
  • Seeing, hearing, or feeling things that are not there.
  • Seizures (convulsions), or fainting.
  • Trouble urinating or painful urination.
  • Unable to sweat or feeling overheated.

If you notice these less serious side effects, talk with your doctor:

  • Back pain or aching joints.
  • Blurred vision, dry eyes, or eyes sensitive to light.
  • Constipation, diarrhea, nausea or vomiting, heartburn, or stomach pain or upset.
  • Dizziness or headache.
  • Dry mouth or nose.
  • Lack or loss of strength.
  • Problems having an erection.
  • Runny or stuffy nose.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/4/2014
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