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Cefuroxime (Oral route)

Pronunciation:

sef-ue-ROX-eem AX-e-til

Brand Names:

  • Ceftin

Dosage Forms:

  • Powder for Suspension
  • Tablet

Classifications:

Therapeutic—

Antibiotic

Pharmacologic—

2nd Generation Cephalosporin

Uses of This Medicine:

Cefuroxime is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Before Using This Medicine:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies—

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Children—

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cefuroxime in children. However, safety and efficacy have not been established in infants younger than 3 months of age.

Older adults—

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefuroxime in the elderly.

Pregnancy—

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast-feeding—

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Other medicines—

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other interactions—

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems—

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Colitis (inflammation in gut), history of or
  • Diarrhea, severe, history of—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.
  • Phenylketonuria (PKU)—The oral liquid form of this medicine contains phenylalanine, which can make this condition worse.

Proper Use of This Medicine:

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Ceftin® oral liquid works differently than Ceftin® tablets, even at the same dose (number of milligrams). Do not switch from the tablets to the oral liquid unless your doctor tells you to.

The oral liquid form must be taken with meals, while the tablet form may be given with or without food.

Swallow the tablets whole. Do not break, crush, or chew it.

Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

Dosing—

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For infections:
    • For oral dosage form (film-coated tablets):
      • Adults and teenagers—250 to 500 milligrams (mg) two times a day for 10 days. Gonorrhea is treated with a single 1-gram (g) dose.
      • Children (who can swallow the tablets)—250 mg two times a day for 10 days.
      • Children (who cannot swallow the tablets)—Use is not recommended.
    • For oral dosage form (suspension):
      • Children 3 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 20 to 30 milligrams (mg) per kilogram (kg) of body weight per day divided into two doses, taken for 10 days. However, the dose is usually not more than 1000 mg.
      • Infants up to 3 months—Use and dose must be determined by your doctor.

Missed dose—

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the oral liquid in the refrigerator. Throw away any unused medicine after 10 days.

Store the tablets in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Precautions While Using This Medicine:

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Cefuroxime may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you or your child have any medical tests, tell the medical doctor in charge that you are using this medicine. The results of some tests may be affected by this medicine.

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
Chills
diarrhea
fever
general feeling of illness or discomfort
headache
itching of the vagina or genital area
pain during sexual intercourse
rigidity
sweating
thick, white vaginal discharge with no odor or with a mild odor
Less common
Black, tarry stools
chest pain
cough
loose stools
painful or difficult urination
shortness of breath
sore throat
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
unusual bleeding or bruising
unusual tiredness or weakness
Rare
Back, leg, or stomach pains
bladder pain
bleeding gums
bloody or cloudy urine
body aches or pain
burning while urinating
dark urine
difficulty with breathing
ear congestion
fast, pounding, or irregular heartbeat or pulse
frequent urge to urinate
general body swelling
loss of appetite
loss of voice
lower back or side pain
nasal congestion
nausea or vomiting
nosebleeds
pain or tenderness around the eyes and cheekbones
pale skin
pink or red urine
sneezing
stuffy or runny nose
swelling of the joints
swollen glands
tightness of chest or wheezing
white or brownish vaginal discharge
white patches in the mouth or throat or on the tongue
white patches with diaper rash
yellowing of the eyes or skin
Incidence not known
Blistering, peeling, or loosening of the skin
bloody, black, or tarry stools
clay-colored stools
cough or hoarseness
coughing up blood
decrease in urine output or decrease in urine-concentrating ability
feeling of discomfort
fever with or without chills
general feeling of tiredness or weakness
high fever
hives
increased menstrual flow or vaginal bleeding
joint or muscle pain
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
light-colored stools
paralysis
prolonged bleeding from cuts
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
red or black, tarry stools
red or dark brown urine
red skin lesions, often with a purple center
red, irritated eyes
seizures
swollen lymph glands
swollen or painful glands
unpleasant breath odor
upper right abdominal or stomach pain
vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
Bad, unusual, or unpleasant (after) taste
change in taste
diaper rash
Rare
Abdominal or stomach cramps
acid or sour stomach
belching
bloated
difficulty with moving
excess air or gas in the stomach or intestines
flushing or redness of the skin
full feeling
gas in the stomach
heartburn
indigestion
irritability
irritation or soreness of the mouth
itching skin
muscle pain or stiffness
muscle spasm of the neck
passing gas
restlessness
sleepiness or unusual drowsiness
stomach discomfort, upset, or pain
swelling of the tongue
thirst
trouble sitting still
unusually warm skin
watering of the mouth and drooling
weight loss
Incidence not known
Hives or welts
redness of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Last Updated: 11/4/2014

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