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Nitrofurazone (Topical route)

Pronunciation:

nye-troe-FURE-a-zone

Brand Names:

  • Furacin

Dosage Forms:

  • Ointment
  • Solution
  • Cream

Classifications:

Therapeutic—

Antibacterial

Uses of This Medicine:

Nitrofurazone is used to treat burns that have become infected. It is also used to treat skin infections due to skin grafts. It works by killing bacteria or preventing their growth.

Nitrofurazone may be applied directly to the skin or placed on a gauze pad that will cover the skin.

This medicine is available only with your doctor's prescription.

Before Using This Medicine:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies—

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Children—

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of nitrofurazone in children with use in other age groups.

Older adults—

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of nitrofurazone in the elderly with use in other age groups.

Other medicines—

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other interactions—

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems—

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Kidney disease—Certain ingredients (polyethylene glycols) in the topical solution and the soluble dressing may be absorbed through the skin and may not be eliminated from the body normally in patients with kidney function impairment, which may increase the chance of side effects. Nitrofurazone cream does not contain polyethylene glycol.

Proper Use of This Medicine:

Apply sufficient medication to affected area or place medication on gauze and cover the affected area.

Dosing—

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For cream dosage form:
    • Burns or skin infections:
      • Adults—Apply directly to the lesion, or place on gauze that will cover the lesion, once daily or every few days, depending on the usual dressing technique of the affected area.
      • Children—Use and dose must be determined by your doctor.
  • For soluble dressing dosage form:
    • Burns or skin infections:
      • Adults—Apply directly to the lesion or place on gauze that will cover the lesion, depending on the usual dressing technique of the affected area.
      • Children—Use and dose must be determined by your doctor.
  • For topical solution dosage form:
    • Burns:
      • Adults—Apply directly to the burn.
      • Children—Use and dose must be determined by your doctor.

Missed dose—

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage—

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Keep away from alkaline materials, such as soap and ammonia.

Precautions While Using This Medicine:

If your burn or skin infection does not improve, or if it becomes worse, check with your health care professional.

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common
Itching
rash
swelling

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Last Updated: 4/4/2014

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