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Cholera vaccine (Injection route)

Pronunciation:

KOL-er-a VAX-een

Dosage Forms:

  • Suspension
  • Injectable

Classifications:

Therapeutic—

Vaccine

Uses of This Medicine:

Cholera

is a serious disease that can cause death. It is caused by a germ called Vibrio cholerae, and is spread most often through infected food or water. If you are traveling to cholera-infected areas, avoid eating uncooked food, especially fish and shellfish, and peel fruit yourself. Avoid water that may be infected; carbonated bottled water and carbonated soft drinks are safe.

Cholera is rare in the U.S. and other areas of the world that have good water and sewage (waste) systems. However, it is a problem in parts of the world that do not have such systems. If you are traveling to cholera-infected areas (e.g., developing countries of Africa, Asia, and Latin America) cholera vaccine may help protect you from cholera.

Cholera vaccine given by injection may help prevent cholera, but provides only 25 to 50% protection. Therefore, it is very important to avoid infected persons and food and water that may be infected, even if you have received the vaccine.

To get the best possible protection against cholera, you should complete the vaccine dosing schedule before you travel to areas where you may be exposed to cholera.

If you will be staying in parts of the world where cholera is a problem, you should get a booster (repeat) dose of the vaccine every 6 months.

Cholera vaccine is to be administered only by or under the supervision of a doctor.

Before Using This Medicine:

In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:

Allergies—

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Children—

Cholera vaccine is not recommended for infants up to 6 months of age.

Older adults—

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information about the use of cholera vaccine in the elderly.

Pregnancy—

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast-feeding—

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other medicines—

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this vaccine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Yellow Fever Vaccine

Other interactions—

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems—

The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Severe illness with fever—The symptoms of this condition may be confused with the side effects of the vaccine

Proper Use of This Medicine:

Dosing—

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

As long as the likelihood of exposure to cholera continues, you may need a booster dose every 6 months.

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
Difficulty in breathing or swallowing
hives
itching, especially of soles or palms
reddening of skin, especially around ears
swelling of eyes, face, or inside of nose
unusual tiredness or weakness (sudden and severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
Fever
general feeling of discomfort or illness
headache
pain, redness, or swelling at place of injection

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Last Updated: 11/4/2014

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