What is it?
Ginkgo is an herbal medicine used to improve memory and concentration, as well as to treat dementia (loss of thinking skills), confusion, ringing in the ears, premenstrual syndrome (PMS), blood circulation problems, vision problems, and vertigo (dizziness).
Other names for ginkgo include: Fossil tree, Kew tree, Maidenhair tree, Ginkgo biloba, Oriental plum tree, and Silver apricot.
Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.
Tell your doctor if you
- are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement).
- are pregnant or plan to become pregnant while using this medicine.
- are breastfeeding.
- have a history of seizures (26).
- have any other health problems, such as high blood pressure or heart or blood vessel disease.
Talk with your caregiver about how much ginkgo you should take. The amount depends on the strength of the medicine and the reason you are taking ginkgo. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.
To store this medicine:
Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.
Drug and Food Interactions:
Do not take ginkgo without talking to your doctor first if you are taking:
- Blood thinning medicine (examples: warfarin (Coumadin(R)); clopidogrel (Plavix(R)); aspirin; enoxaparin (Lovenox(R)), dalteparin (Fragmin(R))) (9,23,27)
- Medicines used for pain or swelling (examples: ibuprofen (Advil(R), Motrin(R)); naproxen (Aleve(R), Naprosyn(R)); nabumetone (Relafen(R))) (28)
- Medicine for depression (examples: sertraline (Zoloft(R)); paroxetine (Paxil(R)); fluoxetine (Prozac(R)); citalopram (Celexa(R)))
- Medicines for depression or Parkinson's disease (examples: isocarboxazid (Marplan(R)); phenelzine (Nardil(R)); selegiline (Eldepryl(R), Emsam(R), Zelapar(R)); tranylcypromine (Parnate(R))) (30)
- Medicine used for high blood pressure or chest pain (nifedipine (Adalat(R), Procardia(R))) (10)
- Medicine used for high blood pressure or swelling ("water pills") (examples: chlorothiazide (Diuril(R)); hydrochlorothiazide (Esidrix(R), Hydro-Par(R), Microzide(TM))) (17)
- Medicine used for seizures or certain types of pain (examples: phenytoin (Dilantin(R)); carbamazepine (Tegretol(R)); gabapentin (Neurontin(R)); valproic acid (Depakote(R)), Depakene(R))) (29)
- Medicine given before surgery or medical procedures to help you become relaxed or sleepy (example: midazolam) (33)
- Medicine used to treat bacterial infections and certain types of skin infections or pneumonia. This medicine is an antibiotic (example: linezolid (Zyvox(R)) (32)
- Medicine used to treat diabetes mellitus (example: tolbutamide (Tol-Tab(R)) (34)
- Insulin (15)
- Amiodarone (Nexterone(R)) (35)
- Buspirone (BuSpar(R)) (21)
- Papaverine (Para-Time SR(R)) (28)
- Risperidone (Risperidal(R)) (31)
- Trazodone (Desyrel(R)) (18)
- St John's wort (21)
- Sulfinpyrazone (Anturane(R)) (23,24)
- Omeprazole (Prilosec(R)) (22)
- Before taking ginkgo, tell your doctor if you are pregnant or breastfeeding.
- Before having any surgery, tell your doctor that you take ginkgo. Ginkgo may cause bleeding problems during or after surgery. You may need to stop taking ginkgo before having surgery (4,25).
Call your doctor right away if you have any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hand, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, or rash
- Blistering, peeling, red skin rash
- Seizure or coma
Other Side Effects:
You may have the following side effects, but this medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.
- Fast or pounding heartbeat
- Nausea (upset stomach) or headaches
- Unusual bruising or bleeding
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12. Fachinformation: Roekan(R):, ginkgo extract: Intersan Gmbh, Ettlingen, Germany; 1996.
13. Fachinformation: Tebonin(R), ginkgo extract. Dr Willmar Schwae Gmbh & Co, Karlsruhe, Germany; 1996.
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20. Norred CL & Finlayson CA: Hemorrhage after the preoperative use of complementary and alternative medicines. AANA J 2000; 68:217-220.
21. Spinella M & Eaton LA: Hypomania induced by herbal and pharmaceutical psychotropic medicines following mild traumatic brain injury. Brain Injury 2002; 16(4):359-367.
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24. Matthews MK: Association of Ginkgo biloba with intracerebral hemorrhage. Neurology 1998; 50:1933-1934.
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32. Product Information: Zyvox(R) IV injection, oral tablets, oral suspension, linezolid IV injection, oral tablets, oral suspension. Pharmacia & Upjohn Company, New York, NY, 2008.
33. Robertson SM , Davey RT , Voell J , et al: Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects. Curr Med Res Opin 2008; 24(2):591-599.
34. Uchida S, Yamada H, Li XD, et al: Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers. J Clin Pharmacol 2006; 46(11):1290-1298.
35. Product Information: NEXTERONE(R) IV injection, amiodarone hydrochloride IV injection. Baxter Healthcare Corporation, Deerfield, IL, 2011.
Last Updated: 11/4/2014